Photochemical conversion of 7-dehydrocholesterol into vitamin D3 in rat skins.
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چکیده
منابع مشابه
Provitamin D3 in tissues and the conversion of cholesterol to 7-dehydrocholesterol in vivo.
The discovery that the absorption bands at 293, 281-5 and 271 m,u. (Heilbron, Kamm & Morton, 1926, 1927) present in fractions obtained in the recrystallization of cholesterol were shown very strongly by ergosterol (Rosenheim & Webster, 1927) focused interest on the latter and culminated in the isolation ofcalciferol (vitamin D2). Some time later it was recognized that 7-dehydrocholesterol was a...
متن کاملBinding of 7-dehydrocholesterol to sterol carrier protein and vitamin D3 effect.
It was confirmed that delta 5,7-sterol delta 7-reductase activity was suppressed by cholecalciferol (vitamin D3) in the enzyme system consisted of microsomes and sterol carrier protein (SCP). The enzyme activity was significantly decreased in the combination with microsomes obtained from either vitamin D-deficient or vitamin D3-treated rat liver and with SCP obtained from vitamin D3-treated rat...
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Background: Several lines of evidence suggest that oxidized LDL (Ox-LDL) scavenger receptors play a crucial role in the genesis and progression of diabetic atherosclerosis. This study aimed to elucidate the effect of vitamin D3 on gene expression of lectin-like oxidized LDL receptor-1 (LOX-1), scavenger receptor-A (SR-A), Cluster of Differentiation 36 (CD36), and Cluster of Differentiation 68 (...
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Introduction: Atherosclerosis has been identified as the most agents for premature death and disability and of its injuries is growing masses of fatty materials with fibrous connective tissue and deposition of calcium salts and other blood materials. To do research on atherosclerosis, in creating hypercholesterolemia animal model is important. Methods: In this wxperimental study, 4 groups of...
متن کاملThe Fate of the 6a-Hydrogen of 5&holest-7-en-3@ol in the Conversion to 7-Dehydrocholesterol by Rat Liver Microsomes*
2-14C-Mevalonic acid has been incubated with a rat liver homogenate in the presence of the inhibitor frans-1,4bis(2 chlorobenzylaminoethyl) cyclohexanedihydrochloride yielding 1,7,15,22 ,26-14CS-cholesta-5,7-dien3@-01, which was reduced with lithium and ammonia to 14Cs-5ar-cholest-7en-30-01 (A’-cholestanol). Separation from endogenous cholesterol was achieved by oxidation with chromic acid, and...
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ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 1977
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.23.165